The innate immune system in transplantation
نویسندگان
چکیده
منابع مشابه
The innate immune system in transplantation.
The vertebrate innate immune system consists of inflammatory cells and soluble mediators that comprise the first line of defense against microbial infection and, importantly, trigger antigen-specific T and B cell responses that lead to lasting immunity. The molecular mechanisms responsible for microbial non-self recognition by the innate immune system have been elucidated for a large number of ...
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Conrad A. Farrar1, Jerzy W. Kupiec-Weglinski2, and Steven H. Sacks1 MRC Centre for Transplantation, Division of Transplantation Immunology and Mucosal Biology, King’s College London School of Medicine at Guy’s, King’s College and St. Thomas’ Hospitals, London SE1 9RT, United Kingdom The Dumont-UCLATransplant Center, Division of Liver and Pancreas Transplantation, Department of Surgery, David Ge...
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The innate immune system ; is an important subsystem of the overall immune response system that comprises the cells and mechanisms that defend the host from infection by other organisms. The cells of the innate system recognize and respond to pathogens in a generic way, but, unlike the adaptive immune system, the system does not confer long-lasting or protective immunity to the host. Innate imm...
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Studies of the immune mechanisms of allograft rejection have predominantly focused on the adaptive immune system that includes T cells and B cells. Recent investigations into the innate immune system, which recognizes foreign antigens through more evolutionarily primitive pathways, have demonstrated a critical role of the innate immune system in the regulation of the adaptive immune system. Inn...
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The Human Immune System (HIS) is a complex network composed of specialized cells, tissues, and organs that is responsible for protecting the organism against diseases caused by distinct pathogenic agents, such as viruses, bacteria and other parasites. The first line of defence against pathogenic agents consists of physical barriers of skin and the mucous membranes. If the pathogenic agents brea...
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ژورنال
عنوان ژورنال: Seminars in Immunology
سال: 2011
ISSN: 1044-5323
DOI: 10.1016/j.smim.2011.06.006